The reference site for Olsalazine

Olsalazine is an anti-inflammatory drug used in the treatment of inflammatory bowel disease such as ulcerative colitis. It is sold under the name Dipentum.

WHAT IS Olsalazine?

Olsalazine is an anti-inflammatory drug used in the treatment of inflammatory bowel disease and ulcerative colitis.

The exact way that olsalazine works is unknown, but it is believed to reduce the actions of a substance in the body that causes inflammation, tissue damage, and diarrhea.

It is sold under the brand name Dipentum®.


Brand Name(s): Dipentum
CAS nº: 15722-48-2
(ole SAL a zeen)


Product Info

The sections below will provide you with more specific information and guidelines related to olsalazine and its correct use. Please read them carefully.

FDA Information

Olsalazine gained Food and Drug Administration approval in 1990.

Generic olsalazine capsules are not yet available. A prescription is required for this medicine.

Please visit the official site of the FDA for further information.

Why is this medication prescribed?

Olsalazine is a derivative of salicylic acid, and is an anti-inflammatory agent.

It reduces inflammation inside the bowel, diarrhea (stool frequency), rectal bleeding, abdominal pain, and pain associated with ulcerative colitis. More importantly, it helps to prevent recurring inflammation from taking place.

Other uses for this medicine

This medication has not been approved for any alternative uses other than those mentioned in the product information section.

Dosage and using this medicine

Olsalazine comes as a capsule to be taken orally.

Take olsalazine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Each dose should be taken with a full glass of water.

Additionally, take this medication with food in evenly divided doses as directed.

What special precautions should I follow?


Tell your doctor if you have any type of kidney disease. You may need a lower dose or special monitoring during therapy with olsalazine.

Olsalazine may increase the effects of warfarin (Coumadin®), which could lead to bleeding. Tell your doctor if you are taking warfarin before starting therapy with olsalazine.

Drugs other than those listed here may also interact with olsalazine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

It is not known whether this medicine will harm an unborn baby. Do not take this medicine without first talking to your doctor if you are pregnant.

Furthermore, it is not known whether olsalazine passes into breast milk. Do not take this medicine without first talking to your doctor if you are breast-feeding a baby.

There are no restrictions on foods, beverages, or activities during therapy with olsalazine unless your doctor directs otherwise.

What should I do if I forget a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose.

Never take a double dose of this medication to make up for a missed one, and it will not speed up the recovery rate.

What side effects can this medication cause?

If you experience any of the following serious side effects, stop taking olsalazine and seek emergency medical attention:

an allergic reaction (difficulty breathing, closing of your throat, swelling of your lips, tongue, or face, or hives)
worsening colitis (fever, abdominal pain, cramping, or bloody diarrhea)

Note: Diarrhea is a commonly experienced side effect of olsalazine therapy. Call your doctor as soon as possible if you experience diarrhea.

Other, less serious side effects may be more likely to occur.Continue to take olsalazine and talk to your doctor if you experience:

abdominal cramping, nausea, or vomiting
headache or dizziness
a rash

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What storage conditions are needed for this medicine?

Always keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Please remember to throw away any medication that is outdated or no longer needed. If you have any questions, talk to your pharmacist about the proper disposal of your medication.

In case of an emergency/overdose

In the case of an overdose, call your local poison control center on 1-800-222-1222. However, if the victim has collapsed or is not breathing, please call the local emergency services immediately on 911.

Symptoms of overdose may include:


Product Images


Below you will find images and specific information on the principal types of olsalazine that exist, including their respective brand name(s), strength, inscription codes, manufacturers and/or distributors.

The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.

Strength(s): 250 MG
Manufacturer: CELLTECH (UCB PHARM.)

Strength(s): 500 MG
Manufacturer: CELLTECH (UCB PHARM.)

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